Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358072 | 0.84 | ALOX5 (0.53) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10359321 | 0.82 | ALOX5 (0.52) | ALDH1A1HPGDKMT2ASMN1; SMN2MAPT | |
| SCHEMBL10641462 | 0.82 | ALOX5 (0.53) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9175427 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11111617 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2ASMN1; SMN2MAPT | |
| SCHEMBL9175312 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10640776 | 0.77 | MAPT (0.53) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10358900 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10359352 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10358385 | 0.76 | SMN1; SMN2 (0.67) | ALDH1A1HPGDHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |