Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012043 | 0.90 | GABRA1 (0.52) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL1194767 | 0.86 | GABRA1 (0.47) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL1413853 | 0.83 | SRD5A1 (0.49) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL323547 | 0.80 | XDH (0.54) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL45432 | 0.79 | GABRA1 (0.53) | GABRA1GABRB2SRD5A1XDHGAA | |
| Hydrogen Sulfide SCHEMBL6721312 | 0.78 | XDH (0.52) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL9297409 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL7943871 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL1005361 | 0.77 | GABRA1 (0.55) | GABRA1GABRB2SRD5A1XDHGAA | |
| SCHEMBL9472065 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2SRD5A1XDHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4972039-A | POLYCARBONATES FORMED BY CATALYTIC POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0224769-B1 | CROSSLINKABLE POLYCYCLIC POLYCARBONATE OLIGOMERS AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4888411-A | BISHALOFORMATE AND TETRAPHENOL, ALKALI METAL HYDROXIDE, TERTIARY AMINE | GENERAL ELECTRIC COMPANY (US) | 1989-12-19 | — | — | US | disclosed |
| US-4794160-A | CYCLIC POLYMERS; POLYTHIOCARBONATES; TETRAPHENOL MODIFIERS | GENERAL ELECTRIC COMPANY (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0283838-A2 | Method for preparing crosslink polyclic polycarbonate oligomer compositions with supression of aqueous emulsion formation | GENERAL ELECTRIC COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4755586-A | Method for preparing crosslinkable polycyclic polycarbonate oligomer compositions with suppression of aqueous emulsion formation | GENERAL ELECTRIC COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0224769-A2 | Crosslinkable polycyclic polycarbonate oligomers and methods for their preparation | GENERAL ELECTRIC COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |