Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555632 | 0.83 | — | — | |
| SCHEMBL5584855 | 0.83 | — | — | |
| SCHEMBL5608067 | 0.77 | SUCNR1 (0.42) | SUCNR1KDM4EGMNNLMNAPMP22 | |
| SCHEMBL5194126 | 0.77 | SUCNR1 (0.42) | SUCNR1KDM4EGMNNLMNAPMP22 | |
| SCHEMBL5195767 | 0.77 | SUCNR1 (0.42) | SUCNR1KDM4EGMNNLMNAPMP22 | |
| SCHEMBL8539572 | 0.69 | SUCNR1 (0.62) | SUCNR1KDM4EGMNNLMNAPMP22 | |
| SCHEMBL14115855 | 0.68 | MEN1 (0.46) | KDM4ELMNAPMP22TSHR | |
| SCHEMBL510704 | 0.67 | TRIM24 (0.44) | — | |
| SCHEMBL6126 | 0.66 | GABRP (0.46) | KDM4ELMNAPMP22TSHR | |
| SCHEMBL9234017 | 0.64 | TRIM24 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0213547-A1 | Cyclohexanealkanoic acids | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |