SCHEMBL5608067

SCHEMBL5608067

O=C(O)[C@@H]1O[C@H]1C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.42
GRM2 Q14416 1/20 0.35
LMNA P02545 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TFPI2 P48307 2/20 0.34
GMNN O75496 1/20 0.34
PMP22 Q01453 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
PPP1CA P62136 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
HSD11B1 P28845 1/20 0.33
GRIK1 P39086 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5194126 1.00 SUCNR1 (0.42) SUCNR1GRM2LMNAKDM4ETFPI2
SCHEMBL5195767 1.00 SUCNR1 (0.42) SUCNR1GRM2LMNAKDM4ETFPI2
SCHEMBL5584855 0.88
SCHEMBL8555632 0.88
SCHEMBL5196895 0.75 RIPK1 (0.35) TSHRALDH1A1
SCHEMBL5608543 0.75 SMN1; SMN2 (0.39) TP53TSHRALDH1A1
SCHEMBL8539572 0.74 SUCNR1 (0.62) SUCNR1LMNAKDM4ETFPI2GMNN
SCHEMBL5608730 0.74 EPHX1 (0.39) HTT
SCHEMBL5608583 0.72 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL5608576 0.71 GAA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169944-B2 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2007-01-30 US claimed
US-20040063979-A1 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2004-04-01 US claimed
EP-1403260-A2 Optically active epoxy compounds and processes for their production Tosoh Corporation (JP) 2004-03-31 EP claimed
US-7169944-B2 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2007-01-30 US disclosed
JP-2004284992-A PRODUCTION METHOD FOR OPTICALLY ACTIVE TRANS-3-CYCLOHEXYL-OXIRANECARBOXYLIC ACID DAIICHI FINE CHEMICAL CO LTD 2004-10-14 JP disclosed
US-20040063979-A1 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403260-A2 Optically active epoxy compounds and processes for their production Tosoh Corporation (JP) 2004-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063979-A1 Optically active epoxy compounds and processes for their production CYP51A1, CYP11B1, PTGES SUCNR1 4192/4885GRM2 4362/4885LMNA 1688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.