Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359236 | 0.91 | IMPDH1 (0.36) | PTGS1FNTAFNTBIMPDH1 | |
| SCHEMBL10359555 | 0.91 | IMPDH1 (0.36) | PTGS1FNTAFNTBIMPDH1 | |
| SCHEMBL10359299 | 0.82 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL10359748 | 0.76 | PPARG (0.39) | PTGS1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2240425 | 0.67 | CYP3A4 (0.31) | — | |
| SCHEMBL2558530 | 0.63 | LMNA (0.46) | ALDH1A1TSHR | |
| SCHEMBL5919687 | 0.61 | PRKCA (0.38) | TSHR | |
| SCHEMBL9754775 | 0.59 | LMNA (0.40) | ALDH1A1TSHR | |
| SCHEMBL6138341 | 0.59 | OPRM1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL11245204 | 0.59 | LMNA (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | claimed |