Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648133 | 0.92 | MAP1LC3B (0.44) | POLBMAPK1L3MBTL1 | |
| SCHEMBL1766102 | 0.91 | MAPT (0.47) | ALDH1A1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL12648386 | 0.89 | MAPT (0.53) | ALDH1A1SMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL12648266 | 0.89 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTHSD17B10MAPT | |
| SCHEMBL10360042 | 0.87 | RAB9A (0.38) | ALDH1A1MAPTRAB9ACYP2C9GAA | |
| SCHEMBL9589037 | 0.82 | MAP1LC3B (0.40) | ALDH1A1SMN1; SMN2POLBHSD17B10MAPT | |
| SCHEMBL12648264 | 0.82 | KMT2A (0.44) | ALDH1A1SMN1; SMN2POLBALOX12HTT | |
| SCHEMBL10533930 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBALOX12HTT | |
| SCHEMBL10531260 | 0.81 | MAP1LC3B (0.41) | POLBHSD17B10MAPK1L3MBTL1 | |
| SCHEMBL10533958 | 0.81 | HSD17B10 (0.38) | ALDH1A1SMN1; SMN2POLBHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202042-B1 | CYCLOHEXANE-1,3-DIONE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PROCESSES FOR PREPARING THEM, AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1990-05-09 | — | — | EP | disclosed |
| US-4746350-A | Herbicidal bis(cyclohexane-1,3-dione)derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-24 | — | — | US | disclosed |
| EP-0202042-A1 | Cyclohexane-1,3-dione derivatives, compositions containing them, processes for preparing them, and their use as herbicides and plant growth regulators | ICI AUSTRALIA LIMITED (AU) | 1986-11-20 | — | — | EP | disclosed |