Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360302 | 0.88 | NOTUM (0.43) | RXRAGRIN1GRIN2BNOTUMEPHX2 | |
| SCHEMBL10361148 | 0.87 | NOTUM (0.44) | RXRAGRIN1GRIN2BNOTUMEPHX2 | |
| SCHEMBL10361126 | 0.87 | BCHE (0.36) | GRIN1GRIN2BKMT2AMEN1MAPT | |
| SCHEMBL10360343 | 0.86 | HSD17B10 (0.45) | RXRAGRIN1GRIN2BNOTUMEPHX2 | |
| SCHEMBL10361078 | 0.85 | PKM (0.40) | NOTUMPOLBKMT2AMEN1MAPT | |
| SCHEMBL10361130 | 0.85 | KCNJ6 (0.40) | RXRAGRIN1GRIN2BNOTUMEPHX2 | |
| SCHEMBL10360325 | 0.85 | RXRA (0.40) | RXRAGRIN1GRIN2BNOTUMEPHX2 | |
| SCHEMBL10360316 | 0.84 | ALDH1A1 (0.43) | RXRAGRIN1GRIN2BNOTUMPOLB | |
| SCHEMBL10361173 | 0.82 | ACACB (0.45) | RXRAGRIN1GRIN2BNOTUMCYP1A2 | |
| SCHEMBL10361307 | 0.75 | MAPT (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |