SCHEMBL10360684

SCHEMBL10360684

CNC(=O)C(C)Oc1ncn(-c2cc(C)ccc2C)n1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.35
EIF4H Q15056 1/20 0.35
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 4/20 0.34
TP53 P04637 3/20 0.34
NPSR1 Q6W5P4 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.32
HCAR1 Q9BXC0 1/20 0.32
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360286 0.77 MAPT (0.51) ALDH1A1MAPTTP53SMN1; SMN2HPGD
SCHEMBL10360405 0.75 LMNA (0.41) ALDH1A1KMT2AMEN1MAPTTP53
SCHEMBL10360305 0.74 KMT2A (0.45) ALDH1A1KMT2AMEN1MAPTTP53
SCHEMBL10360294 0.72 SCN9A (0.36) ALDH1A1KMT2AMAPTKDM4E
SCHEMBL10361130 0.71 KCNJ6 (0.40) KMT2AMEN1MAPTNPSR1LMNA
SCHEMBL10360402 0.70 SMN1; SMN2 (0.41) ALDH1A1KMT2AMEN1MAPTNPSR1
SCHEMBL10360730 0.69 TSHR (0.45) ALDH1A1KMT2AMEN1MAPTSMN1; SMN2
SCHEMBL10361303 0.69 MAPT (0.40) ALDH1A1KMT2AMAPTTP53SMN1; SMN2
SCHEMBL10360399 0.69 MAPT (0.44) ALDH1A1KMT2AMEN1MAPTTP53
SCHEMBL10360673 0.68 MEN1 (0.44) ALDH1A1KMT2AMEN1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4931083-A Plant growth regulating triazoles ELI LILLY AND COMPANY (US) 1990-06-05 US disclosed
EP-0227284-A1 Plant Growth regulating triazoles ELI LILLY AND COMPANY (US) 1987-07-01 EP disclosed