Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113907 | 0.94 | PDK2 (0.32) | PDK2 | |
| SCHEMBL16687347 | 0.91 | ORAI1 (0.34) | ORAI1P2RX7CA1CA2 | |
| SCHEMBL1034275 | 0.91 | PTGES (0.35) | LMNAHPGDORAI1P2RX7TP53 | |
| SCHEMBL3108617 | 0.90 | MEN1 (0.36) | PDK2MAPT | |
| SCHEMBL871002 | 0.90 | KMT2A (0.36) | PDK2CDK1MAPT | |
| SCHEMBL3102889 | 0.90 | EGLN1 (0.34) | ORAI1P2RX7 | |
| SCHEMBL21863693 | 0.90 | PDK2 (0.39) | PDK2HPGDBRD4CNR1ORAI1 | |
| SCHEMBL1035116 | 0.90 | ALDH1A1 (0.39) | LMNAHPGDCNR1TP53MAPT | |
| SCHEMBL883221 | 0.89 | HPGD (0.31) | HPGDORAI1P2RX7 | |
| SCHEMBL3108150 | 0.89 | PDK2 (0.34) | PDK2CNR1KCNA3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140038821-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-06 | — | — | US | claimed |
| US-20130029845-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-31 | — | — | US | claimed |
| US-7964204-B2 | Isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-21 | — | — | US | claimed |
| EP-1973888-B1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2011-01-26 | — | — | EP | claimed |
| US-20100234219-A1 | Isoxazolines for Controlling Invertebrate Pests | CORTEVA AGRISCIENCE LLC | 2010-09-16 | — | — | US | claimed |
| US-8871941-B2 | 8-bromo-5-quinolinecarboxaldehyde oxime | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140249314-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-04 | — | — | US | disclosed |
| US-20140038821-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-06 | — | — | US | disclosed |
| US-8552218-B2 | Isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20130029845-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-31 | — | — | US | disclosed |
| US-8231888-B2 | Isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110263641-A1 | Isoxazolines For Controlling Invertebrate Pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-27 | — | — | US | disclosed |
| US-7964204-B2 | Isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-21 | — | — | US | disclosed |
| EP-1973888-B1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2011-01-26 | — | — | EP | disclosed |
| US-20100234219-A1 | Isoxazolines for Controlling Invertebrate Pests | CORTEVA AGRISCIENCE LLC | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249314-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | C1S, C3AR1, CBR3 | PDK2 2835/4885LMNA 2853/4885HPGD 3468/4885 |
| US-20130029845-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | C1S, C3AR1, CBR3 | PDK2 2835/4885LMNA 2853/4885HPGD 3468/4885 |
| US-20100234219-A1 | Isoxazolines for Controlling Invertebrate Pests | C1S, C3AR1, CBR3 | PDK2 2739/4885LMNA 2824/4885HPGD 3550/4885 |
| US-20140038821-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | C1S, C3AR1, CBR3 | PDK2 2835/4885LMNA 2853/4885HPGD 3468/4885 |
| US-20110263641-A1 | Isoxazolines For Controlling Invertebrate Pests | C1S, C3AR1, CBR3 | PDK2 3207/4885LMNA 2912/4885HPGD 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.