Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720043 | 0.76 | RXRA (0.36) | RXRAGRIN1GRIN2B | |
| SCHEMBL10360687 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2LMNAMAPTALOX12HTT | |
| SCHEMBL10361120 | 0.74 | HPGD (0.39) | SMN1; SMN2LMNAMAPTALOX12HTT | |
| SCHEMBL10360684 | 0.70 | PABPC1 (0.35) | SMN1; SMN2LMNAMAPTNPSR1HPGD | |
| SCHEMBL10360403 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTALOX12HTT | |
| SCHEMBL10360360 | 0.69 | MAPT (0.39) | SMN1; SMN2MAPTSCN9ARAB9AKMT2A | |
| SCHEMBL10360720 | 0.68 | ALDH1A1 (0.41) | SMN1; SMN2HTTSCN9AHPGDRAB9A | |
| SCHEMBL10360329 | 0.66 | TDP1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL10361138 | 0.63 | MAPT (0.39) | SMN1; SMN2MAPTRXRAGRIN1GRIN2B | |
| SCHEMBL10361111 | 0.63 | TSHR (0.45) | SMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |