Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642107 | 0.77 | FDPS (0.40) | FDPSMMP2CA12CA1CA2 | |
| SCHEMBL8155018 | 0.77 | FDPS (0.40) | FDPSMMP2CA12CA1CA2 | |
| SCHEMBL5365372 | 0.76 | MMP2 (0.33) | FDPSMMP2CA12CA1CA2 | |
| SCHEMBL2579739 | 0.76 | ALDH1A1 (0.36) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL8131339 | 0.74 | KEAP1 (0.37) | KEAP1NFE2L2ALDH1A1HMGCRCHRM1 | |
| SCHEMBL8140433 | 0.73 | FDPS (0.37) | FDPSMETAP1 | |
| SCHEMBL2696014 | 0.73 | FDPS (0.37) | FDPSMETAP1 | |
| SCHEMBL8154749 | 0.73 | FDPS (0.37) | FDPSMETAP1 | |
| Cyclobutoic Acid SCHEMBL2109852 | 0.72 | CHRM1 (0.46) | KEAP1NFE2L2ALDH1A1HMGCRCHRM1 | |
| SCHEMBL10942267 | 0.71 | ALDH1A1 (0.39) | KEAP1NFE2L2ALDH1A1HMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252880-B1 | HYDROXYPHOSPHONO CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4847017-A | CORROSION RESISTANCE IN WATER SYSTEMS | CIGA-GEIGY CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |