Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361597 | 0.93 | ALOX5 (0.53) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9877044 | 0.88 | ALOX5 (0.61) | ALOX5PTGS1PTGS2 | |
| SCHEMBL10873379 | 0.87 | ALOX5 (0.59) | ALOX5PTGS1PTGS2 | |
| SCHEMBL11816511 | 0.80 | HDAC3 (0.53) | ALOX5 | |
| SCHEMBL11816512 | 0.80 | HDAC3 (0.53) | ALOX5 | |
| SCHEMBL10361683 | 0.79 | MAOB (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9877248 | 0.76 | HDAC8 (0.58) | — | |
| SCHEMBL19839341 | 0.75 | HDAC3 (0.43) | — | |
| SCHEMBL11817850 | 0.75 | TTR (0.58) | ALOX5PTGS2 | |
| SCHEMBL11817862 | 0.75 | TTR (0.58) | ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199151-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-11-07 | — | — | EP | disclosed |
| US-4623661-A | HYDROXAMIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0199151-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | disclosed |