Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839316 | 0.88 | PTPN1 (0.54) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL11816511 | 0.81 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL11816512 | 0.81 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL10362090 | 0.75 | ALOX5 (0.52) | — | |
| SCHEMBL19838780 | 0.73 | ALDH1A1 (0.39) | CYP1B1ALDH1A1MAPTHPGDMAOA | |
| SCHEMBL4412144 | 0.73 | LMNA (0.59) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL2396441 | 0.73 | LMNA (0.59) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL11817850 | 0.73 | TTR (0.58) | CYP3A4MAOB | |
| SCHEMBL11817862 | 0.73 | TTR (0.58) | CYP3A4MAOB | |
| SCHEMBL28362150 | 0.73 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026811-A2 | ANTIFUNGAL AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2018-02-08 | — | — | WO | disclosed |