Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803446 | 0.90 | TGM2 (0.56) | ALDH1A1TGM2KMT2AMTNR1AMEN1 | |
| SCHEMBL10362590 | 0.90 | MTNR1A (0.46) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL10818993 | 0.86 | GAA (0.54) | ALDH1A1HTTSMN1; SMN2TGM2KMT2A | |
| SCHEMBL10363161 | 0.84 | TGM2 (0.51) | ALDH1A1SMN1; SMN2TGM2KMT2AGAA | |
| SCHEMBL10810049 | 0.84 | HDAC8 (0.45) | ALDH1A1TGM2KMT2AMTNR1AMEN1 | |
| SCHEMBL10364043 | 0.83 | TGM2 (0.50) | ALDH1A1HPGDSMN1; SMN2TGM2KMT2A | |
| SCHEMBL10362427 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HTTHPGDSMN1; SMN2TGM2 | |
| SCHEMBL10363944 | 0.83 | LMNA (0.59) | ALDH1A1HPGDSMN1; SMN2TGM2KMT2A | |
| SCHEMBL10806562 | 0.83 | TGM2 (0.53) | ALDH1A1HTTTGM2KMT2AMEN1 | |
| SCHEMBL10804625 | 0.83 | HCRTR1 (0.44) | ALDH1A1HPGDSMN1; SMN2TGM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |