Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363161 | 0.87 | TGM2 (0.51) | TGM2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10363995 | 0.87 | LMNA (0.53) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL10363212 | 0.86 | TGM2 (0.49) | TGM2HCRTR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL10803992 | 0.85 | ALDH1A1 (0.54) | TGM2HCRTR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL10803446 | 0.84 | TGM2 (0.56) | TGM2HCRTR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10362457 | 0.84 | LMNA (0.58) | TGM2HDAC6HCRTR1ALDH1A1KDM4E | |
| SCHEMBL10809320 | 0.83 | GAA (0.45) | HDAC3HDAC1HDAC2HDAC6HCRTR1 | |
| SCHEMBL10362443 | 0.82 | GAA (0.49) | TGM2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10818366 | 0.82 | TGM2 (0.50) | TGM2HCRTR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL10806798 | 0.82 | KDM4E (0.56) | TGM2HCRTR1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |