Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361981 | 0.77 | HTT (0.54) | HTTCA1CA2CA7POLB | |
| SCHEMBL10361959 | 0.71 | LMNA (0.62) | HTTCA1CA2CA7POLB | |
| SCHEMBL15920165 | 0.71 | CACNA2D1 (0.68) | HTTPOLBMAPTCACNA2D1CACNA1B | |
| SCHEMBL10361979 | 0.70 | CACNA2D1 (0.43) | HTTSMN1; SMN2MAPTCACNA2D1CACNA1B | |
| SCHEMBL19977194 | 0.70 | ME2 (0.51) | HTTCA1CA2CA7SMN1; SMN2 | |
| SCHEMBL10363478 | 0.70 | HTT (0.57) | HTTCA1CA2CA7POLB | |
| SCHEMBL10362010 | 0.69 | LMNA (0.66) | HTTCA1CA2CA7POLB | |
| SCHEMBL10362411 | 0.69 | LMNA (0.58) | HTTPOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL10361518 | 0.68 | LMNA (0.61) | HTTCA1CA2CA7POLB | |
| SCHEMBL4274014 | 0.68 | CACNA2D1 (0.65) | MAPTCACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | claimed |