Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113636 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2ACACBHDAC3HTT | |
| SCHEMBL29873370 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2ACACBHDAC3HTT | |
| SCHEMBL5783367 | 0.75 | PKM (0.55) | ALDH1A1SMN1; SMN2LMNAACACBHDAC3 | |
| SCHEMBL21690018 | 0.75 | PKM (0.55) | ALDH1A1SMN1; SMN2LMNAACACBHDAC3 | |
| SCHEMBL2297609 | 0.75 | PKM (0.55) | ALDH1A1SMN1; SMN2LMNAACACBHDAC3 | |
| SCHEMBL31711179 | 0.75 | PKM (0.55) | ALDH1A1SMN1; SMN2LMNAACACBHDAC3 | |
| SCHEMBL25355987 | 0.74 | PLK1 (0.50) | ALDH1A1SMN1; SMN2LMNAPABPC1ACACB | |
| SCHEMBL31688796 | 0.74 | PLK1 (0.50) | ALDH1A1SMN1; SMN2LMNAPABPC1ACACB | |
| SCHEMBL25355989 | 0.74 | PLK1 (0.50) | ALDH1A1SMN1; SMN2LMNAPABPC1ACACB | |
| SCHEMBL934232 | 0.74 | FCER2 (0.53) | ALDH1A1SMN1; SMN2LMNAACACBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908349-A | Tetrahydronaphthalene aldehyde compound | GIVAUDAN CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |