Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809452 | 0.93 | KDM4E (0.51) | MTNR1AMTNR1BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL10805489 | 0.90 | ZDHHC2 (0.55) | ALDH1A1KDM4E | |
| SCHEMBL10363985 | 0.89 | ZDHHC20 (0.49) | MTNR1AMTNR1BKMT2ANPC1RECQL | |
| SCHEMBL10809535 | 0.87 | MTNR1A (0.47) | MTNR1AMTNR1BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL10362447 | 0.87 | HPGD (0.60) | ALDH1A1L3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL10364151 | 0.86 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1KMT2ANPC1 | |
| SCHEMBL10807803 | 0.86 | ALDH1A1 (0.47) | MTNR1AMTNR1BALDH1A1KMT2AKDM4E | |
| SCHEMBL10362351 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL10362343 | 0.85 | POLB (0.60) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL10364060 | 0.85 | MAOB (0.48) | KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |