Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228585 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2ATGM2MTNR1A | |
| SCHEMBL10362453 | 0.79 | TGM2 (0.48) | ALDH1A1LMNAKMT2ATGM2NAMPT | |
| SCHEMBL448580 | 0.76 | IDO1 (0.51) | GPR84IDO1 | |
| SCHEMBL7846356 | 0.75 | HTR2C (0.53) | ALDH1A1KMT2AGPR84IDO1HTR2C | |
| SCHEMBL11025088 | 0.75 | HTR2C (0.49) | ALDH1A1KMT2AEPHX2GPR84IDO1 | |
| SCHEMBL452347 | 0.74 | IDO1 (0.50) | GPR84IDO1 | |
| SCHEMBL28997008 | 0.74 | MTNR1A (0.39) | LMNATGM2MTNR1AF13A1TGM1 | |
| SCHEMBL449978 | 0.74 | IDO1 (0.53) | GPR84IDO1 | |
| SCHEMBL10804424 | 0.74 | KCNA3 (0.53) | ALDH1A1LMNAKMT2ATGM2ZDHHC20 | |
| SCHEMBL9626216 | 0.73 | IDO1 (0.51) | GPR84IDO1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |