Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.31 |
| ▸ | MICA | Q29983 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1075802 | 0.73 | CCR10 (0.43) | CCR10BRD4CREBBPGFERHPGDS | |
| SCHEMBL1075995 | 0.66 | CCR10 (0.61) | CCR10 | |
| SCHEMBL25412012 | 0.58 | ENPP2 (0.38) | CCR10GFERHPGDSHRH3 | |
| Hydrochloric Acid SCHEMBL1312700 | 0.58 | DPP7 (0.47) | CCR10GFER | |
| SCHEMBL17229398 | 0.57 | NOS1 (0.39) | BRD4CREBBPCHRM1 | |
| SCHEMBL17221380 | 0.57 | NOS1 (0.39) | BRD4CREBBPCHRM1 | |
| SCHEMBL1036704 | 0.56 | ALOX5 (0.34) | HTR2C | |
| Hydrochloric Acid SCHEMBL1313841 | 0.56 | CCR10 (0.36) | CCR10 | |
| SCHEMBL27372101 | 0.56 | DPP4 (0.48) | CCR10GFERHRH3 | |
| SCHEMBL27249717 | 0.55 | RBP4 (0.61) | HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276731-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | Boehringer Ingelheim International GmbH (DE) | 2011-01-26 | — | — | EP | claimed |
| WO-2009126675-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | WO | claimed |