Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363306 | 0.92 | CTSL (0.39) | ANPEPCTSLFNTAPGGT1BFNTB | |
| SCHEMBL10362642 | 0.89 | CNR2 (0.39) | ANPEPCTSLFNTAPGGT1BFNTB | |
| SCHEMBL10748220 | 0.86 | REN (0.38) | — | |
| SCHEMBL10364253 | 0.81 | FNTA (0.39) | CTSLFNTAPGGT1BFNTB | |
| SCHEMBL10363367 | 0.79 | CTSL (0.37) | ANPEPCTSLFNTAPGGT1BFNTB | |
| SCHEMBL10364218 | 0.78 | MYC (0.47) | ATM | |
| SCHEMBL10362476 | 0.68 | TACR1 (0.53) | ATM | |
| SCHEMBL10780120 | 0.68 | OPRD1 (0.44) | ANPEPCTSL | |
| SCHEMBL10782324 | 0.67 | CTSL (0.42) | ANPEPCTSL | |
| SCHEMBL10748217 | 0.66 | TACR1 (0.51) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |