Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 4/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364398 | 0.86 | TDP1 (0.37) | — | |
| SCHEMBL10362476 | 0.80 | TACR1 (0.53) | MEN1KMT2A | |
| SCHEMBL10363306 | 0.78 | CTSL (0.39) | — | |
| SCHEMBL10748217 | 0.77 | TACR1 (0.51) | MEN1KMT2AOXTRAVPR2AVPR1A | |
| SCHEMBL10362642 | 0.76 | CNR2 (0.39) | MEN1KMT2A | |
| SCHEMBL10364359 | 0.74 | TACR1 (0.38) | RENPSMB9OXTRAVPR2AVPR1A | |
| SCHEMBL10363304 | 0.73 | TACR1 (0.52) | MEN1KMT2A | |
| SCHEMBL1371611 | 0.73 | CAPN1 (0.45) | KMT2AOXTRAVPR2AVPR1AAVPR1B | |
| SCHEMBL1371614 | 0.73 | CAPN1 (0.45) | KMT2AOXTRAVPR2AVPR1AAVPR1B | |
| SCHEMBL1372348 | 0.73 | CTRB1 (0.57) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |