Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 12/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 12/20 | 0.35 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405790 | 0.87 | ACHE (0.42) | ACHECDK5CDK5R1 | |
| SCHEMBL9583081 | 0.78 | CDK1 (0.44) | — | |
| SCHEMBL9584953 | 0.75 | CDC20 (0.35) | — | |
| SCHEMBL10404901 | 0.75 | CDK5 (0.38) | CDK5CDK5R1 | |
| SCHEMBL10364108 | 0.74 | ACHE (0.40) | ACHENPR3 | |
| SCHEMBL9584563 | 0.73 | HDAC6 (0.41) | — | |
| SCHEMBL9583770 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL9583904 | 0.73 | CYP1A2 (0.39) | — | |
| SCHEMBL9583124 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL9584849 | 0.71 | CDK5 (0.41) | CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152965-B1 | PROCESS FOR PREPARING 2,6-SUBSTITUTED-9-(1,3-DIHYDROXY-2-PROPOXY-MENTHYL)-PURINES AND CERTAIN DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| US-4621140-A | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0152965-A2 | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxy-menthyl)-purines and certain derivatives | SYNTEX (U.S.A.) INC. (US) | 1985-08-28 | — | — | EP | disclosed |