Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816711 | 0.81 | CYP1A2 (0.37) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL9583770 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL9583081 | 0.77 | CDK1 (0.44) | MAPK1ABCB11POLA1POLGFAP | |
| SCHEMBL9584953 | 0.75 | CDC20 (0.35) | MAPK1ABCB11POLA1POLGFAP | |
| SCHEMBL9583124 | 0.73 | KDM4E (0.41) | — | |
| SCHEMBL10364403 | 0.73 | ACHE (0.38) | — | |
| SCHEMBL9583917 | 0.71 | CYP1A2 (0.50) | CYP1A2CYP2D6MAPK1ABCB11POLA1 | |
| SCHEMBL9584677 | 0.71 | CYP1A2 (0.48) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL10813829 | 0.69 | ADORA2A (0.45) | CYP1A2 | |
| SCHEMBL9583879 | 0.69 | ADORA2A (0.48) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |