Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364688 | 0.83 | ADRA1A (0.43) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10363913 | 0.83 | ADRA1A (0.47) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10362923 | 0.83 | ADRA1A (0.49) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10364479 | 0.82 | ADRA1A (0.48) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10363021 | 0.82 | ADRA1A (0.46) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10364366 | 0.81 | ADRA1A (0.47) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10363777 | 0.81 | LMNA (0.54) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10364816 | 0.80 | NPSR1 (0.48) | ADRA1ALMNAADRB2ADRB1HTR1A | |
| SCHEMBL10363890 | 0.78 | ADRB2 (0.44) | LMNAADRB2OPRK1SLC6A3CYP1A2 | |
| SCHEMBL10362823 | 0.77 | ADRA1A (0.43) | ADRA1ALMNAADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185814-B1 | PHENYLSERINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4695580-A | Phenylserine derivatives and processes for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0185814-A2 | Phenylserine derivatives and processes for their preparation | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |