Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364366 | 0.92 | ADRA1A (0.47) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10362923 | 0.90 | ADRA1A (0.49) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10363913 | 0.88 | ADRA1A (0.47) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10362983 | 0.87 | ALDH1A1 (0.48) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10363021 | 0.86 | ADRA1A (0.46) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10362823 | 0.84 | ADRA1A (0.43) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10363063 | 0.84 | ADRB2 (0.49) | SMN1; SMN2LMNAADRA1AADRB2ADRB1 | |
| SCHEMBL10364688 | 0.80 | ADRA1A (0.43) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10364481 | 0.80 | ADRA1A (0.49) | NPSR1SMN1; SMN2LMNAADRA1AADRB2 | |
| SCHEMBL10362958 | 0.79 | HIF1A (0.48) | ADRA1AHTR1AADRA2ASLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185814-B1 | PHENYLSERINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4695580-A | Phenylserine derivatives and processes for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0185814-A2 | Phenylserine derivatives and processes for their preparation | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |