SCHEMBL103659

SCHEMBL103659

C[Si](C)(C)C#CCCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19878389 0.85
SCHEMBL790240 0.83 ALDH1A1 (0.30)
SCHEMBL789558 0.81 ALDH1A1 (0.33)
SCHEMBL1535208 0.79 LMNA (0.36)
SCHEMBL15786347 0.76 THRB (0.39)
SCHEMBL16420274 0.75 RAB9A (0.33)
SCHEMBL20639270 0.75
SCHEMBL140849 0.75
SCHEMBL29410227 0.74
SCHEMBL29410225 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039285-A Bisindole crown ether diamine and preparation method and application thereof 西南科技大学 2024-11-29 CN claimed
CN-118852686-A Epoxy resin film and preparation method thereof 西南科技大学 2024-10-29 CN claimed
CN-108264694-B Anti-skid rubber 浙江安宝乐科技有限公司 2020-09-04 CN claimed
CN-111441054-A High-acid high-salt corrosion inhibitor suitable for low-temperature part of oil refining device 丁双龙 2020-07-24 CN claimed
CN-108485061-A A kind of technique producing extrusion coating paper using polyolefin feed back 温州大学苍南研究院 2018-09-04 CN claimed
CN-106864077-A A kind of express delivery list of information security 金华职业技术学院 2017-06-20 CN claimed
US-20260109677-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS INC (US) 2026-04-23 US disclosed
US-20260062397-A1 2-DIARYLMETHYL-4-AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS ATUX ISKAY LLC (US) 2026-03-05 US disclosed
US-12522571-B2 Compounds, devices, and uses thereof SIGILON THERAPEUTICS, INC. (US) 2026-01-13 US disclosed
US-12522575-B2 2-diarylmethyl-4-aminotetrahydropyran derivatives and related compounds as anticancer, antiinflammatory, antifibrotic and neuroprotective agents ATUX ISKAY LLC (US) 2026-01-13 US disclosed
US-20250376455-A1 2-DIARYLMETHYL-4-AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS ATUX ISKAY LLC (US) 2025-12-11 US disclosed
CN-119039285-B Bisindole crown ether diamine and preparation method and application thereof 西南科技大学 2025-07-11 CN disclosed
US-12208088-B2 Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof GENENTECH, INC. (US) 2025-01-28 US disclosed
EP-0291673-B1 TETRAHYDROPYRIDINE OXIMES, A PROCESS FOR THEIR PREPARATION AND USE THEREOF AS CHOLINERGIC AGENTS WARNER-LAMBERT COMPANY (US) 1993-06-02 EP disclosed
US-5073561-A N-substituted-pyridinyl oximes WARNER-LAMBERT COMPANY (US) 1991-12-17 US disclosed
US-4929734-A ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS WARNER-LAMBERT COMPANY (US) 1990-05-29 US disclosed
US-4798841-A COGNITION ACTIVATORS, ANALGESICS WARNER-LAMBERT COMPANY (US) 1989-01-17 US disclosed
EP-0291673-A1 Tetrahydropyridine oximes, a process for their preparation and use thereof as cholinergic agents WARNER-LAMBERT COMPANY (US) 1988-11-23 EP disclosed
US-4710508-A ANALGESICS WARNER-LAMBERT COMPANY (US) 1987-12-01 US disclosed
US-4536592-A ANTISECRETORY AGENT G. D. SEARLE & CO. (US) 1985-08-20 US disclosed