Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.53 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239727 | 0.81 | PSMD14 (0.59) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL1337689 | 0.77 | HTR1A (0.61) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL16133354 | 0.77 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL16132603 | 0.76 | MAPT (0.56) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL26073093 | 0.74 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL29035107 | 0.74 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL30423646 | 0.74 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL574340 | 0.74 | MAPT (0.55) | CYP3A4MAPTSMN1; SMN2MAPK1KDM4E | |
| SCHEMBL3820470 | 0.74 | CYP3A4 (0.57) | HTR1AADRA1AALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL1812882 | 0.73 | KDM4E (0.56) | ALDH1A1L3MBTL1CYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138773-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1990-08-29 | — | — | EP | claimed |
| EP-0138773-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1990-08-29 | — | — | EP | disclosed |