Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897041 | 0.86 | RXRA (0.50) | NOTUML3MBTL1HTTNR4A3POLB | |
| SCHEMBL6963674 | 0.86 | POLB (0.55) | MAPK14L3MBTL1XDHNR4A3POLB | |
| SCHEMBL10896747 | 0.85 | L3MBTL1 (0.44) | NOTUMMAPK14L3MBTL1NPBWR1NR4A3 | |
| SCHEMBL10891390 | 0.85 | MAPK14 (0.54) | NOTUMMAPK14L3MBTL1NR4A3POLB | |
| SCHEMBL10897037 | 0.85 | KMT2A (0.53) | NOTUML3MBTL1HTTNR4A3KEAP1 | |
| SCHEMBL10366862 | 0.85 | MAPK14 (0.46) | NOTUMMAPK14IRAK4NPBWR1MCHR1 | |
| SCHEMBL10894270 | 0.82 | POLB (0.50) | NOTUMPOLBMAPTSMN1; SMN2KEAP1 | |
| SCHEMBL31252567 | 0.82 | MAPT (0.67) | NOTUMMAPK14POLBMAPTSMN1; SMN2 | |
| SCHEMBL26125572 | 0.82 | MAPT (0.67) | NOTUMMAPK14POLBMAPTSMN1; SMN2 | |
| SCHEMBL31252561 | 0.81 | NFE2L2 (0.68) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151867-B1 | CYANOPYRAZOLE HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4631343-A | Cyanopyrazole intermediates | ELI LILLY AND COMPANY (US) | 1986-12-23 | — | — | US | disclosed |
| US-4589905-A | TERRESTRIAL AND AQUATIC APPLICATIONS | ELI LILLY AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151867-A2 | Cyanopyrazole herbicides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |