Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | ESD | P10768 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287680 | 0.84 | ALDH1A1 (0.43) | HTR1AHTR7DRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9867723 | 0.83 | CD274 (0.43) | CD274PDCD1GRM7 | |
| SCHEMBL10367909 | 0.79 | GRM5 (0.36) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10365420 | 0.79 | MAPT (0.41) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9868353 | 0.78 | SLC11A2 (0.49) | CD274PDCD1HTR1AHTR2AHTR2C | |
| SCHEMBL10366230 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL9601978 | 0.78 | MEN1 (0.35) | ALDH1A1 | |
| SCHEMBL10368047 | 0.76 | POLB (0.44) | HTR1AHTR2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10368016 | 0.76 | NR3C2 (0.37) | ALDH1A1 | |
| SCHEMBL10366098 | 0.76 | ALDH1A1 (0.43) | HTR1AHTR2AHTR2CHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1193222-A | — | — | None | — | — | JP | disclosed |
| EP-0190367-B1 | BENZO ADH BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-17 | — | — | EP | disclosed |
| JP-H01193222-A | AGENT FOR ENHANCING HOST DEFENSE ABILITY | YOSHITOMI PHARMACEUT IND LTD | 1989-08-03 | — | — | JP | disclosed |
| US-4782057-A | ANTIDOTES FOR OVERSEDATION, ANXIOLYTICS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0190367-A1 | BENZO ADh BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |