Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868353 | 0.85 | SLC11A2 (0.49) | CD274PDCD1CYP19A1GRM7 | |
| SCHEMBL10366227 | 0.83 | CD274 (0.50) | CD274PDCD1GRM7 | |
| SCHEMBL9866418 | 0.81 | HSP90AA1 (0.39) | MIFESR2CYP19A1CYP26A1ESR1 | |
| SCHEMBL9865424 | 0.79 | MIF (0.40) | MIFESR2CYP19A1CYP26A1ESR1 | |
| SCHEMBL10367579 | 0.79 | PRKCZ (0.41) | ESR2CYP19A1CYP26A1ESR1 | |
| SCHEMBL9866508 | 0.79 | HTR1A (0.43) | CD274PDCD1BCHEACHE | |
| SCHEMBL9864910 | 0.78 | L3MBTL1 (0.38) | ESR2CYP19A1CYP26A1ESR1 | |
| SCHEMBL9865443 | 0.78 | MAPT (0.43) | MIFBCHEACHE | |
| SCHEMBL9865351 | 0.76 | HTR1A (0.53) | — | |
| Hydrochloric Acid SCHEMBL10445023 | 0.75 | HTR1A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |