Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 2/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866508 | 0.85 | HTR1A (0.43) | SLC11A2PDCD1CD274HTR2AHTR2C | |
| SCHEMBL9865443 | 0.85 | MAPT (0.43) | HTR2AHTR2CHTR1AMEN1KMT2A | |
| SCHEMBL9867723 | 0.85 | CD274 (0.43) | PDCD1CD274GRM7CYP19A1 | |
| SCHEMBL10366166 | 0.81 | MEN1 (0.43) | HTR2AHTR2CMEN1NPC1RAB9A | |
| SCHEMBL9865351 | 0.81 | HTR1A (0.53) | HTR2AHTR2CHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10445024 | 0.80 | HTR1A (0.51) | HTR2AHTR2CHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10445023 | 0.80 | HTR1A (0.51) | HTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL10366227 | 0.78 | CD274 (0.50) | PDCD1CD274HTR2AHTR2CHTR1A | |
| SCHEMBL10365961 | 0.75 | APP (0.43) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL10367982 | 0.73 | MEN1 (0.48) | MEN1NPC1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |