SCHEMBL10366355

SCHEMBL10366355

C=CCC(CC=C)(C(=O)O)c1ccccc1C=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
TSHR P16473 2/20 0.60
HTT P42858 2/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
CYP2C19 P33261 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.32
GAA P10253 1/20 0.32
AKT1 P31749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2718019 0.79 ALDH1A1 (0.62) ALDH1A1TSHRHTTKMT2AMEN1
SCHEMBL7769347 0.75 ALDH1A1 (1.00) ALDH1A1TSHRHTTKMT2AMEN1
SCHEMBL444608 0.75 ALDH1A1 (0.57) ALDH1A1TSHRHTTKMT2AMEN1
SCHEMBL8020617 0.74 ALDH1A1 (0.55) ALDH1A1TSHRHTTKMT2AMEN1
SCHEMBL8020606 0.74 ALDH1A1 (0.55) ALDH1A1TSHRHTTKMT2AMEN1
SCHEMBL28857552 0.71 PIN1 (0.38) ALDH1A1TSHRKMT2AMEN1LMNA
SCHEMBL6754118 0.70 KMT2A (0.44) ALDH1A1TSHRHTTPTGDR2KMT2A
SCHEMBL4797170 0.70 ALDH1A1 (0.69) ALDH1A1TSHRHTTKMT2AMEN1
SCHEMBL9748549 0.70 ALDH1A1 (0.80) ALDH1A1TSHRHTTKMT2AMEN1
Trifluoroacetic Acid SCHEMBL1922217 0.69 NFKB1 (0.56) KMT2AMEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0237769-B1 BENZALDEHYDE-DIALKYL ACETALS BAYER AG (DE) 1990-04-04 EP disclosed
EP-0237769-A2 Benzaldehyde-dialkyl acetals BAYER AG (DE) 1987-09-23 EP disclosed