Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998536 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL18672266 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL18672249 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL21511152 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL10769830 | 0.79 | KMT2A (0.61) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL18672268 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL10366469 | 0.79 | GAA (0.50) | SMN1; SMN2LMNAHTTNPSR1KMT2A | |
| SCHEMBL9233810 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL9236523 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL12722376 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193853-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |