SCHEMBL441682

SCHEMBL441682

CCN(CCOCCN(CC)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.35
MMP1 P03956 8/20 0.34
MMP2 P08253 8/20 0.34
MMP9 P14780 8/20 0.34
MMP8 P22894 8/20 0.34
MMP13 P45452 8/20 0.34
CA1 P00915 6/20 0.34
F2 P00734 3/20 0.33
PRSS1 P07477 3/20 0.33
PRSS2 P07478 3/20 0.33
PRSS3 P35030 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438310 0.93 F2 (0.33) CA2MMP1MMP2MMP9MMP8
SCHEMBL10438316 0.93 MMP1 (0.33) CA2MMP1MMP2MMP9MMP8
SCHEMBL29457183 0.93 MMP1 (0.33) CA2MMP1MMP2MMP9MMP8
SCHEMBL10438318 0.93 MMP1 (0.33) CA2MMP1MMP2MMP9MMP8
SCHEMBL5168754 0.93 F2 (0.33) CA2MMP1MMP2MMP9MMP8
SCHEMBL5152620 0.89 CA1 (0.34) CA2MMP1MMP2MMP9MMP8
SCHEMBL9326862 0.85 CA2 (0.32) CA2MMP1MMP2MMP9MMP8
SCHEMBL29910639 0.84 CA2 (0.43) CA2MMP1MMP2MMP9MMP8
SCHEMBL2888010 0.83 MMP1 (0.33) CA2MMP1MMP2MMP9MMP8
SCHEMBL10358857 0.83 MMP1 (0.33) CA2MMP1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240159781-A1 SANDWICH ASSAY FOR SMALL MOLECULES SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-05-16 US disclosed
US-11913965-B2 Sandwich assay for small molecules SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-02-27 US disclosed
US-20230160880-A1 PRETREATMENT AGENT IN NON-AGGLUTINATION ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2023-05-25 US disclosed
US-11592439-B2 Pretreatment agent in non-agglutination assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2023-02-28 US disclosed
EP-4036572-A1 METHODS FOR DETECTION OF IMMUNOSUPPRESSANT DRUGS Siemens Healthcare Diagnostics Inc. (US) 2022-08-03 EP disclosed
US-11377483-B2 Sandwich assay design for small molecules SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2022-07-05 US disclosed
EP-2176658-B1 METHODS FOR DETECTION OF IMMUNOSUPPRESSANT DRUGS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2022-06-01 EP disclosed
US-20210199677-A1 SANDWICH ASSAY FOR SMALL MOLECULES SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2021-07-01 US disclosed
EP-3234607-B1 SANDWICH ASSAY DESIGN FOR SMALL MOLECULES SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2021-04-28 EP disclosed
US-20210087255-A1 SANDWICH ASSAY DESIGN FOR SMALL MOLECULES SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2021-03-25 US disclosed
WO-2011163340-A1 REDUCTION IN FALSE RESULTS IN ASSAY MEASUREMENTS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-12-29 WO disclosed
US-8084223-B2 Detection of false results in assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-12-27 US disclosed
US-20110136136-A1 Methods For Detection Of Hydrophobic Drugs SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-06-09 US disclosed
US-7910378-B2 Methods for detection of hydrophobic drugs SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-03-22 US disclosed
US-20100240073-A1 DETECTION OF FALSE RESULTS IN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC., A CORPORATION OF CALIFORNIA (US) 2010-09-23 US disclosed
US-7790401-B2 Methods for detection of immunosuppressant drugs SIEMENS HEALTHCARE DIAGNOSTICS (US) 2010-09-07 US disclosed
EP-2217926-A1 METHODS FOR DETECTION OF HYDROPHOBIC DRUGS Siemens Healthcare Diagnostics Inc. (US) 2010-08-18 EP disclosed
WO-2009079374-A1 METHODS FOR DETECTION OF HYDROPHOBIC DRUGS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-06-25 WO disclosed
US-20090155929-A1 METHODS FOR DETECTION OF HYDROPHOBIC DRUGS SIEMENS HEALTHCARE DIAGNOSTICS INC., A CORPORATION OF CALIFORNIA (US) 2009-06-18 US disclosed
US-20090042223-A1 METHODS FOR DETECTION OF IMMUNOSUPPRESSANT DRUGS DADE BEHRING INC., A CORPORATION OF DELAWARE (US) 2009-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377483-B2 Sandwich assay design for small molecules SHBG, SERPINA6, SPR CA2 3805/4885MMP1 3366/4885MMP2 1732/4885
US-20210087255-A1 SANDWICH ASSAY DESIGN FOR SMALL MOLECULES SHBG, SERPINA6, SPR CA2 3805/4885MMP1 3366/4885MMP2 1732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.