Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232591 | 0.84 | HTR2A (0.47) | CA2 | |
| SCHEMBL5232580 | 0.84 | HTR2A (0.47) | CA2 | |
| SCHEMBL6943821 | 0.82 | CA2 (0.56) | TMEM97SIGMAR1CA2NAMPTHTR7 | |
| SCHEMBL18395904 | 0.82 | CA2 (0.56) | TMEM97SIGMAR1CA2NAMPTHTR7 | |
| SCHEMBL6933031 | 0.82 | ALDH1A1 (0.52) | TMEM97SIGMAR1CA2HTR7 | |
| SCHEMBL9098184 | 0.82 | ALDH1A1 (0.52) | TMEM97SIGMAR1CA2HTR7 | |
| SCHEMBL2493185 | 0.82 | ALDH1A1 (0.52) | TMEM97SIGMAR1CA2HTR7 | |
| SCHEMBL516278 | 0.81 | TDP1 (0.56) | — | |
| SCHEMBL25691508 | 0.81 | ADRA1A (0.34) | TMEM97SIGMAR1L3MBTL1ADRA1AADRA1B | |
| SCHEMBL22710272 | 0.80 | TDP1 (0.59) | TMEM97SIGMAR1CA2ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388950-A2 | New 1,3-dioxolan-4-yl derivatives of 2-picolylamine | J. URIACH & CIA. S.A. (ES) | 1990-09-26 | — | — | EP | disclosed |