SCHEMBL516278

SCHEMBL516278

O=C(OCC1CO1)Oc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
MGLL Q99685 6/20 0.52
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8886446 0.87 MGLL (0.45) MGLLSMN1; SMN2
SCHEMBL10015231 0.87 MGLL (0.49) TDP1MGLLALDH1A1TP53CYP3A4
SCHEMBL10367241 0.86 TDP1 (0.42) TDP1MGLL
SCHEMBL230593 0.82 L3MBTL1 (0.41) TDP1MGLL
SCHEMBL13796548 0.81 MGLL (0.45) MGLL
SCHEMBL4838795 0.81 ALDH1A1 (0.51) TDP1MGLLALDH1A1TP53CYP3A4
SCHEMBL10367463 0.81 TMEM97 (0.47)
SCHEMBL10015229 0.81 MGLL (0.40) TDP1MGLLSMN1; SMN2
SCHEMBL10366578 0.81 MGLL (0.43) TDP1MGLL
SCHEMBL13771512 0.80 ALDH1A1 (0.40) MGLLALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2012-02-02 US disclosed
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2012-02-02 US disclosed
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2012-02-02 US disclosed
US-8084553-B2 Curable adhesive compositions, process, and applications TRILLION SCIENCE, INC. (US) 2011-12-27 US disclosed
US-8084553-B2 Curable adhesive compositions, process, and applications TRILLION SCIENCE, INC. (US) 2011-12-27 US disclosed
US-20090181165-A1 Curable adhesive compositions, Process, and applications TRILLION SCIENCE, INC. (US) 2009-07-16 US disclosed
US-20090181165-A1 Curable adhesive compositions, Process, and applications TRILLION SCIENCE, INC. (US) 2009-07-16 US disclosed
US-20090181165-A1 Curable adhesive compositions, Process, and applications TRILLION SCIENCE, INC. (US) 2009-07-16 US disclosed
WO-2009089314-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2009-07-16 WO disclosed
WO-2009089314-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS RBX1, SUZ12, CDH1 TDP1 620/4885MGLL 3210/4885ALDH1A1 429/4885
US-20090181165-A1 Curable adhesive compositions, Process, and applications RBX1, SUZ12, CDH1 TDP1 620/4885MGLL 3210/4885ALDH1A1 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.