Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266907 | 0.95 | CHRM1 (0.49) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL10369501 | 0.93 | CHRM1 (0.51) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL3314224 | 0.88 | CHRM1 (0.40) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL6965129 | 0.85 | CHRM2 (0.47) | CHRM1CHRM2CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL5200635 | 0.84 | ALDH1A1 (0.49) | CHRM1CHRM2CHRM4CHRM3 | |
| Oxalic Acid SCHEMBL10368075 | 0.80 | CHRM2 (0.40) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL10368013 | 0.77 | CHRM2 (0.41) | CHRM1CHRM2CHRM4CHRM3 | |
| Oxalic Acid SCHEMBL7432773 | 0.76 | CHRM2 (0.54) | CHRM1CHRM2CHRM4CHRM3 | |
| Oxalic Acid SCHEMBL6626814 | 0.76 | CHRM2 (0.54) | CHRM1CHRM2CHRM4CHRM3 | |
| Oxalic Acid SCHEMBL7424442 | 0.76 | CHRM2 (0.54) | CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398617-A2 | Process for resolving 1-azabicyclo [2.2.1]heptane-3-carboxylates | MERCK SHARP & DOHME LTD. (GB) | 1990-11-22 | — | — | EP | disclosed |