Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983118 | 0.80 | LMNA (0.34) | — | |
| SCHEMBL19449959 | 0.79 | OPRM1 (0.38) | — | |
| SCHEMBL12000009 | 0.76 | KMT2A (0.39) | — | |
| SCHEMBL21315198 | 0.75 | CYP1A2 (0.41) | — | |
| SCHEMBL4748401 | 0.74 | — | — | |
| SCHEMBL4745759 | 0.73 | — | — | |
| SCHEMBL12312029 | 0.72 | KMT2A (0.37) | KDM4EHTT | |
| SCHEMBL21315293 | 0.71 | KMT2A (0.30) | — | |
| SCHEMBL4748275 | 0.71 | DUT (0.32) | — | |
| SCHEMBL17611966 | 0.70 | KDM4E (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207773-B1 | 7-[(Substituted)amino]-8-[(substituted)carbonyl)-methylamino]-1-oxaspiro[4.5]decanes as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4737493-A | 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0207773-A2 | 7-[(Substituted)amino]-8-[(substituted)carbonyl)-methylamino]-1-oxaspiro[4.5]decanes as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |