Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 3/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.33 |
| ▸ | HTR3B | O95264 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367467 | 0.82 | MAPT (0.44) | PTGS2MEN1KMT2AACHESRD5A1 | |
| SCHEMBL10367572 | 0.82 | KDM4E (0.44) | PTGS2MEN1CYP1A2TSHRKMT2A | |
| SCHEMBL10365809 | 0.81 | ACHE (0.38) | PTGS2ACHESRD5A1PTGS1PARP1 | |
| SCHEMBL10366354 | 0.78 | PDE4A (0.40) | PTGS2MEN1CYP1A2TSHRKMT2A | |
| SCHEMBL10365420 | 0.78 | MAPT (0.41) | PTGS2MEN1KMT2ASRD5A1PTGS1 | |
| SCHEMBL9602844 | 0.78 | ACHE (0.35) | PTGS2TSHRACHEPTGS1PARP1 | |
| SCHEMBL10365856 | 0.76 | APP (0.44) | MEN1TSHRKMT2A | |
| SCHEMBL10366227 | 0.75 | CD274 (0.50) | GRM7HTR1AHTR7HTR2AHTR2C | |
| SCHEMBL9738376 | 0.74 | ACHE (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7287680 | 0.74 | ALDH1A1 (0.43) | PTGS2MEN1CYP1A2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190367-B1 | BENZO ADH BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-17 | — | — | EP | disclosed |
| US-4782057-A | ANTIDOTES FOR OVERSEDATION, ANXIOLYTICS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0190367-A1 | BENZO ADh BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |