Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.35 |
| ▸ | HTR6 | P50406 | 4/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HTR3B | O95264 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840949 | 0.81 | ACHE (0.43) | ACHEBCHEHTR1AHTR6HTR7 | |
| SCHEMBL9738670 | 0.77 | ACHE (0.41) | ACHEBCHEHTR1AHTR6HTR7 | |
| SCHEMBL10367756 | 0.74 | GRM7 (0.33) | ACHEBCHEHTR1AHTR6HTR7 | |
| SCHEMBL9737830 | 0.74 | APP (0.40) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL8840973 | 0.73 | ACHE (0.48) | ACHEBCHEHTR1AHTR6HTR7 | |
| SCHEMBL8840999 | 0.70 | ACHE (0.47) | ACHEBCHEHTR1AHTR6HTR7 | |
| SCHEMBL9737592 | 0.65 | MAPT (0.36) | MEN1ALOX15TSHRKMT2A | |
| SCHEMBL9738054 | 0.65 | MAPT (0.41) | MEN1KMT2A | |
| SCHEMBL9739096 | 0.64 | PDE4A (0.40) | ACHEBCHEHTR1AHTR6HTR7 | |
| SCHEMBL9738208 | 0.62 | GAA (0.34) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |