Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368909 | 0.81 | OPRM1 (0.41) | OPRM1OPRK1CCR2SIGMAR1 | |
| SCHEMBL10366530 | 0.81 | OPRM1 (0.48) | OPRM1OPRK1CCR2 | |
| SCHEMBL10368353 | 0.75 | OPRM1 (0.69) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10367901 | 0.73 | OPRM1 (0.48) | OPRM1OPRK1 | |
| SCHEMBL10367902 | 0.73 | OPRM1 (0.48) | OPRM1OPRK1 | |
| SCHEMBL10366106 | 0.71 | OPRM1 (0.62) | OPRM1OPRK1 | |
| SCHEMBL10366107 | 0.71 | OPRM1 (0.62) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL10683355 | 0.70 | OPRM1 (0.64) | OPRM1OPRK1 | |
| SCHEMBL11531115 | 0.67 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL10368728 | 0.66 | OPRM1 (0.58) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147085-B1 | SUBSTITUTED TRANS-1.2-DIAMINOCYCLOHEXYL AMIDE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |