Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | C5 | P01031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368160 | 0.83 | CACNA2D1 (0.41) | SLC2A1CACNA2D1TACR3TLR7RAB9A | |
| SCHEMBL10367529 | 0.82 | TACR3 (0.39) | SLC2A1CACNA2D1TACR3RAB9AHDAC4 | |
| SCHEMBL10368263 | 0.79 | METAP1 (0.39) | PDE4DTLR7RAB9AMEN1MAPT | |
| SCHEMBL10367948 | 0.79 | CACNA2D1 (0.41) | SLC2A1CACNA2D1TACR3PDE4DTLR7 | |
| SCHEMBL9529634 | 0.77 | TACR3 (0.42) | SLC2A1CACNA2D1TACR3MAPTSMN1; SMN2 | |
| SCHEMBL10368710 | 0.76 | TACR3 (0.43) | SLC2A1CACNA2D1TACR3HDAC4HDAC1 | |
| SCHEMBL10533270 | 0.74 | CACNA2D1 (0.44) | SLC2A1CACNA2D1TACR3RAB9AMEN1 | |
| SCHEMBL9530133 | 0.73 | CACNA2D1 (0.43) | CACNA2D1TACR3TLR7MAPTSMN1; SMN2 | |
| SCHEMBL9528534 | 0.73 | TACR3 (0.42) | CACNA2D1TACR3RAB9ASMN1; SMN2 | |
| Phosphoric Acid SCHEMBL10367954 | 0.73 | TACR3 (0.41) | CACNA2D1TACR3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | claimed |
| US-4711888-A | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-12-08 | — | — | US | claimed |
| EP-0210044-A2 | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-01-28 | — | — | EP | claimed |
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4711888-A | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0210044-A2 | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-01-28 | — | — | EP | disclosed |