Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.58 |
| ▸ | DRD3 | P35462 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.58 |
| ▸ | DRD1 | P21728 | 4/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369438 | 1.00 | CHRM2 (0.58) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL10367407 | 0.89 | CYP2D6 (0.62) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Hydrochloric Acid SCHEMBL10368127 | 0.88 | LMNA (0.62) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Hydrochloric Acid SCHEMBL10368129 | 0.88 | LMNA (0.62) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL7343102 | 0.83 | CHRM2 (0.64) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL7343108 | 0.83 | CHRM2 (0.64) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL10052733 | 0.82 | CYP2D6 (0.71) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Hydrochloric Acid SCHEMBL10367774 | 0.79 | MAPK1 (0.65) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Promethazine SCHEMBL2118132 | 0.78 | CYP2D6 (0.76) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Promethazine SCHEMBL3682874 | 0.78 | CYP2D6 (0.76) | CHRM2HTR1ACHRM1ADRA1AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117302-B1 | PHENOTHIAZINE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |
| EP-0117302-A2 | Phenothiazine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-05 | — | — | EP | disclosed |