Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369766 | 0.90 | ALDH1A1 (0.38) | CYP1A2CYP2C19CYP3A4LMNA | |
| SCHEMBL10367659 | 0.83 | ESR1 (0.43) | SCN9AESR1ESR2 | |
| SCHEMBL10766650 | 0.81 | TRPV1 (0.43) | CYP1A2CYP2D6CYP2C19CYP3A4HDAC1 | |
| SCHEMBL10367691 | 0.80 | ESR1 (0.50) | SCN9ACYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL10503330 | 0.73 | SCN9A (0.45) | SCN9ACYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL10369585 | 0.72 | ALDH1A1 (0.40) | CYP1A2CYP2D6CYP2C19CYP3A4LMNA | |
| SCHEMBL10765068 | 0.70 | ADORA3 (0.43) | — | |
| SCHEMBL10503381 | 0.69 | SCN9A (0.44) | SCN9ACYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL10502715 | 0.69 | SCN9A (0.44) | SCN9ACYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL10367889 | 0.69 | IGF1R (0.42) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | disclosed |