Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRLHR | P49683 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369767 | 0.90 | LMNA (0.48) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL10367658 | 0.83 | ATP1A1 (0.41) | ALDH1A1LMNASMN1; SMN2PRLHRMEN1 | |
| SCHEMBL10367693 | 0.80 | ATP1A1 (0.42) | ALDH1A1LMNASMN1; SMN2PRLHRATP1A1 | |
| SCHEMBL10766646 | 0.78 | FFAR2 (0.49) | ALDH1A1MAPK1TSHRNPSR1 | |
| SCHEMBL10766650 | 0.72 | TRPV1 (0.43) | LMNASMN1; SMN2MEN1KMT2APPARG | |
| SCHEMBL8523815 | 0.71 | AKT1 (0.43) | PRLHRATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL8398268 | 0.69 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL8403294 | 0.69 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL10368708 | 0.68 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10370877 | 0.68 | TACR3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | disclosed |