SCHEMBL10370895

SCHEMBL10370895

Nc1ccc(C(=O)c2ccc(N)cc2C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.56
CDC25B P30305 2/20 0.56
CDC25A P30304 1/20 0.56
TDP1 Q9NUW8 5/20 0.55
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 4/20 0.55
POLB P06746 4/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
THRB P10828 2/20 0.55
RECQL P46063 2/20 0.55
CYP3A4 P08684 2/20 0.55
USP2 O75604 1/20 0.55
PKM P14618 1/20 0.55
APEX1 P27695 1/20 0.55
BLM P54132 1/20 0.55
MCL1 Q07820 1/20 0.55
TNF P01375 1/20 0.55
HSPD1 P10809 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28667299 0.92 KDM4E (0.59) HSD17B10CDC25BCDC25ATDP1ALDH1A1
5-Amino-2-Benzoylbenzoic Acid SCHEMBL31333092 0.91 AKR1C3 (0.62) HSD17B10CDC25BCDC25ATDP1ALDH1A1
5-Amino-2-Benzoylbenzoic Acid SCHEMBL8999371 0.91 AKR1C3 (0.62) HSD17B10CDC25BCDC25ATDP1ALDH1A1
Aminobenzoic Acid SCHEMBL5069244 0.86 TDP1 (0.57) HSD17B10CDC25BCDC25ATDP1ALDH1A1
SCHEMBL9645867 0.85 POLB (0.70) HSD17B10CDC25BCDC25ATDP1ALDH1A1
SCHEMBL29364937 0.83 ALDH1A1 (0.68) HSD17B10CDC25BCDC25ATDP1ALDH1A1
SCHEMBL231377 0.83 ALDH1A1 (0.68) HSD17B10CDC25BCDC25ATDP1ALDH1A1
SCHEMBL11147848 0.83 KDM4E (0.68) HSD17B10CDC25BCDC25ATDP1ALDH1A1
SCHEMBL6447137 0.82 AKR1C3 (0.73) HSD17B10CDC25BCDC25AALDH1A1KDM4E
SCHEMBL2810654 0.81 ALDH1A1 (0.65) HSD17B10CDC25BCDC25ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209259-B1 PHTHALIDE DERIVATIVES AND RECORDING SYSTEM UTILIZING THE SAME KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1990-09-19 EP disclosed
US-4658276-A COLORLESS CHROMOGEN; LEWIS ACID DEVELOPER KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-04-14 US disclosed
EP-0209259-A2 Phthalide derivatives and recording system utilizing the same KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1987-01-21 EP disclosed