SCHEMBL28667299

SCHEMBL28667299

Nc1ccc(C(=O)c2cc(N)ccc2C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
TDP1 Q9NUW8 5/20 0.55
ALDH1A1 P00352 4/20 0.55
POLB P06746 4/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
THRB P10828 2/20 0.55
RECQL P46063 2/20 0.55
CYP3A4 P08684 2/20 0.55
HSD17B10 Q99714 2/20 0.55
USP2 O75604 1/20 0.55
PKM P14618 1/20 0.55
APEX1 P27695 1/20 0.55
BLM P54132 1/20 0.55
MCL1 Q07820 1/20 0.55
TNF P01375 1/20 0.55
HSPD1 P10809 1/20 0.55
CYP2C9 P11712 1/20 0.55
HPGD P15428 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10370895 0.92 HSD17B10 (0.56) KDM4ETDP1ALDH1A1POLBMAPT
SCHEMBL11147848 0.91 KDM4E (0.68) KDM4ETDP1ALDH1A1POLBMAPT
Aminobenzoic Acid SCHEMBL5069244 0.86 TDP1 (0.57) KDM4ETDP1ALDH1A1POLBMAPT
SCHEMBL9645867 0.85 POLB (0.70) KDM4ETDP1ALDH1A1POLBMAPT
SCHEMBL11593777 0.85 KDM4E (0.45) KDM4ETDP1ALDH1A1POLBMAPT
SCHEMBL29364937 0.83 ALDH1A1 (0.68) KDM4ETDP1ALDH1A1POLBMAPT
SCHEMBL231377 0.83 ALDH1A1 (0.68) KDM4ETDP1ALDH1A1POLBMAPT
5-Amino-2-Benzoylbenzoic Acid SCHEMBL31333092 0.83 AKR1C3 (0.62) KDM4ETDP1ALDH1A1POLBMAPT
5-Amino-2-Benzoylbenzoic Acid SCHEMBL8999371 0.83 AKR1C3 (0.62) KDM4ETDP1ALDH1A1POLBMAPT
SCHEMBL6447137 0.82 AKR1C3 (0.73) KDM4EALDH1A1POLBMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113667164-A Polyimide multilayer structure and method for producing same 达胜科技股份有限公司 2021-11-19 CN disclosed