Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2002578 | 0.98 | LMNA (0.96) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| Sulfuric Acid SCHEMBL9010159 | 0.90 | LMNA (0.81) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL6707554 | 0.84 | LMNA (0.71) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL8128010 | 0.84 | LMNA (0.71) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL969167 | 0.79 | ALDH1A1 (0.66) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL1747928 | 0.79 | LMNA (0.66) | LMNAPDE10AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2433144 | 0.78 | LMNA (0.63) | LMNAPDE10AALDH1A1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL28787382 | 0.78 | ALDH1A1 (0.63) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL24858578 | 0.76 | ALDH1A1 (0.61) | LMNAPDE10AALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL21395484 | 0.76 | LMNA (0.61) | LMNAPDE10AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775273-A | Riluzole/ciprofloxacin heterozygote and derivative thereof, and preparation method and application thereof | 赣南医科大学第一附属医院 | 2025-04-08 | — | — | CN | claimed |
| CN-113045993-A | Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof | 西南交通大学 | 2021-06-29 | — | — | CN | claimed |
| CN-110964366-A | Carbon-series conductive filler in water-based conductive electrostatic coating and preparation method thereof | 哈尔滨奥晶云科技有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-106749097-B | A kind of chloro- 2- aminobenzothiazole analog derivative of 6- and its preparation method and application | 温州医科大学 | 2019-07-16 | — | — | CN | claimed |
| CN-107417705-B | Imidazo [2,1-b] benzothiazole compound and its synthetic method | 湘潭大学 | 2019-07-02 | — | — | CN | claimed |
| CN-107973807-A | Triazolobenzothiazole derivative and preparation method and application thereof | 唐山学院 | 2018-05-01 | — | — | CN | claimed |
| CN-107417705-A | Imidazo [2,1 b] benzothiazole compound and its synthetic method | 湘潭大学 | 2017-12-01 | — | — | CN | claimed |
| CN-106749097-A | A kind of aminobenzothiazole analog derivative of 6 chlorine 2 and its preparation method and application | 温州医科大学 | 2017-05-31 | — | — | CN | claimed |
| US-9255182-B2 | Data storage medium and method for high density data storage | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-02-09 | — | — | US | claimed |
| CN-104231659-A | Red thiazole heterocyclic disperse dye compound containing benzoate group and preparation and application thereof | YU XINGYING | 2014-12-24 | — | — | CN | claimed |
| WO-2002053156-A1 | METHOD FOR TREATING GLAUCOMA II B | ALTEON, INC. (US) | 2002-07-11 | — | — | WO | claimed |
| US-20020022622-A1 | Thiazole, imidazole and oxazole compounds and treatments of disorders associated with protein aging | SYNVISTA THERAPEUTICS, INC. | 2002-02-21 | — | — | US | claimed |
| WO-2001052847-A1 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON, INC. (US) | 2001-07-26 | — | — | WO | claimed |
| US-5594145-A | Process for the preparation of 2(3H)-benzothiazolones | HOECHST AG (DE) | 1997-01-14 | — | — | US | claimed |
| EP-0282971-B1 | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents | WARNER LAMBERT CO (US) | 1994-12-28 | — | — | EP | claimed |
| EP-0622362-A1 | Process for the preparation of 2(3H) benzolthiazolons | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-02 | — | — | EP | claimed |
| EP-0331052-A2 | Process for the preparation of imidized acrylic polymers | ELF ATOCHEM ITALIA S.r.l. (IT) | 1989-09-06 | — | — | EP | claimed |
| US-4826860-A | STROKES | WARNER-LAMBERT COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| EP-0282971-A2 | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents | WARNER-LAMBERT COMPANY (US) | 1988-09-21 | — | — | EP | claimed |
| US-3937714-A | 2-AMINOBENZOTHIAZOLES, HYDRAZINE, ACID CATALYSTS | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022622-A1 | Thiazole, imidazole and oxazole compounds and treatments of disorders associated with protein aging | ABAT, NDUFAB1, HSPE1 | LMNA 2059/4885PDE10A 2664/4885ALDH1A1 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.