Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597022 | 0.90 | ATM (0.42) | MEN1KMT2ACCKBRPOLBMAPT | |
| SCHEMBL7828421 | 0.90 | ATM (0.42) | MEN1KMT2ACCKBRPOLBMAPT | |
| SCHEMBL3731770 | 0.89 | MAPT (0.43) | GPR88MEN1KMT2ACCKBRPOLB | |
| Water SCHEMBL8600954 | 0.89 | ATM (0.42) | MEN1KMT2ACCKBRPOLBMAPT | |
| SCHEMBL9814590 | 0.88 | MEN1 (0.38) | MEN1KMT2ACCKBRPOLBMAPT | |
| SCHEMBL10543158 | 0.88 | POLB (0.40) | MEN1KMT2ACCKBRPOLBMAPT | |
| SCHEMBL8600205 | 0.88 | POLB (0.40) | MEN1KMT2ACCKBRPOLBMAPT | |
| SCHEMBL10873072 | 0.88 | ALOX5 (0.44) | — | |
| SCHEMBL10872366 | 0.87 | KMT2A (0.41) | MEN1KMT2AMAPTPDE3ASLC22A6 | |
| SCHEMBL10643650 | 0.86 | MAPT (0.37) | GPR88MEN1KMT2ACCKBRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158494-B1 | PENAM DERIVATIVES AND PROCESS FOR PREPARING THE SAME | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | claimed |
| US-4626384-A | Penam derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1986-12-02 | — | — | US | claimed |
| EP-0158494-A1 | Penam derivatives and process for preparing the same | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-10-16 | — | — | EP | claimed |
| EP-0158494-B1 | PENAM DERIVATIVES AND PROCESS FOR PREPARING THE SAME | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |
| EP-0253337-A2 | Tricyclic cepham compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| US-4626384-A | Penam derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1986-12-02 | — | — | US | disclosed |
| US-4626384-A | Penam derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1986-12-02 | — | — | US | disclosed |
| EP-0158494-A1 | Penam derivatives and process for preparing the same | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-10-16 | — | — | EP | disclosed |
| EP-0158494-A1 | Penam derivatives and process for preparing the same | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-10-16 | — | — | EP | disclosed |
| EP-0061313-B1 | BIS-ESTERS OF 1,1-ALKANEDIOLS WITH 6-BETA-HYDROXYMETHYLPENICILLANIC ACID 1,1-DIOXIDE AND BETA-LACTAM ANTIBIOTICS | PFIZER INC. (US) | 1985-01-16 | — | — | EP | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |